Not content with dominating the TV schedules, The Big Reunionstars 5ive, Atomic Kitten and Blue as guests on their ITV show.
As the song soared up the download charts Ant tweeted: "This is getting ridiculous now!
"What a show last night. Loved it. Aching all over mind!"
And Dec added: "Had the weirdest dream. Dreamt me and Ant did #LetsGetReadyToRhumble live on telly... oh, hang on... that actually happened didn't it?"
Meanwhile, the ever-popular presenters have also revealed that they have got their sights on even-bigger success - and are hatching a plan to crack the US.
The Sunday People claims that the Geordie duo want to take Saturday Night Takeaway across the pond, where they think it will be a success.
Ant said: "We want to take Takeaway to the States as we think it's a great show. We think it would be brilliant for the American audience.
"It could be great. It's the right time to give it a crack. USA Takeaway should work so it's something we think would be really good to do and make happen."

While they've never had a No 1 single, Ant &Dec have been so successful at the National Television Awards that there has [uuid=3d008aaf-b62d-4cc7-bdde-067ff7231de2]been talk of banning them[/uuid].