The rising star of hip-hop had been criticised by Hilton for her tendency to get involved in feuds with other female rappers - and she responded with a tirade of abuse.
According to Digital Spy, he had said: "Some of your music is cute, but your attention-seeking ways are pathetic and hurtful. You drag while others choose to uplift!"
To which she responded: "Whatever bitch, you tried to sign me to ur little bum ass label in '11 with them bulls**t ass artists..."
And she later tweeted: "omg u should just kill yourself... Like for real... lol what a messy f*ggot you are."
She also called him "d**ckbreath" and told him to "gobble a d**k".
But despite her own fans telling her off about the insults, she remained unrepentant.
She wrote: "A f*ggot is not a homosexual male. A f*ggot is any male who acts like a female. There's a BIG difference.
"If u listen to my music and are not offended by the word nigga... We're not gonna go here with this f*ggot s**t... We're just not. Lol."
Perez was on the other end of the same insult a few years ago when he allegedly used the term in a row with Will.I.Am.
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