Their spat started after the former Culture Club singer thanked member Harry Styles on the social-networking site for posing for a photo at The Brit Awards 2013, but slammed Payne.
He wrote: "Top marks to Harry Styles for stopping for a picture with my niece and B*llox's to Liam and the disrespectful w**ker of a minder!
"Stars of the night, Harry Styles, Lana Del Rey, Jessie J. Too many drug f**ked twits to mention elsewhere! Emily Sande was great!
"I reckon Harry Styles will leave One Direction! You heard it here first!"
George later added: "Don't hate on me for keeping the spirit of @onedirection very much alive! I come from a place of love!"
Liam did not take kindly to the 80's icon's comments, branding the Karma Chameleon hitmaker "weird".
He wrote: "@BoyGeorge now now boy lets not tell porkies firstly thanks for getting my name wrong three times secondly then asking me where is liam?... (sic)
"Akward then when you finally got it right saying you wanted Niall instead. if you would have asked me for a picture i would have stopped bro."
Payne added: "I just did what you said and pointed niall out for you so u just keep wearing ur strange hats and enjoy yourself my little Georgie pie... It's still not cool you just look wierd (sic)."
Boy George is yet to comment on Liam's outburst.
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